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IL1B (interleukin 1 β) is an immune-activating cytokine. In presence of infection or cell stress, it gets converted into active mature form.[1]
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Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Mercedes Monteleone et al.
Cytokine, 74(2), 213-218 (2015-04-30)
One of the most poorly understood processes in cell biology is the peculiar ability of specific leaderless proteins to be secreted via ER/Golgi-independent mechanisms ('unconventional protein secretion'). One such leaderless protein is the major immune-activating cytokine, interleukin-1β (IL-1β). Unusual amongst
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