I4153

Anti-Interleukin-12 Receptor β1 antibody produced in goat

affinity isolated antibody, lyophilized powder

• Synonym(s): Anti-IL-12 Receptor β1
• MDL number: MFCD01633525
• UNSPSC Code: 51111800

Properties

• biological source: goat
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: human
• technique(s): indirect ELISA: 0.5-1.0 μg/mL using recombinant human IL-12 Rβ1; western blot: 0.1-0.2 μg/mL using recombinant human IL-12 Rβ1
• UniProt accession no.: P42701
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... IL12RB1(3594)

Description

General description

IL-12 also known as Natural Killer Cell Stimulatory Factor (NKSF) is a 75kD protein that belongs to type I cytokine receptor family and is produced mainly by monocytes and NK cells. IL-12 signals with the help of IL-12 receptor made up of two subunits designated β1 and β2. Interleukin-12 receptor subunit β-1 binds interleukin-12 with low affinity and facilitates in IL12 transduction. Anti-interleukin-12 receptor β1 antibody can be used in ELISA (0.5-1.0 μg/mL) using recombinant human IL-12 Rβ1. Goat anti-interleukin-12 receptor β1 antibody has shown 5% (approx.) cross-reactivity with recombinant mouse IL-12 Rβ1.

Specificity

The antibody shows 5% cross-reactivity with recombinant mouse IL-12 Rβ1.

Immunogen

recombinant human IL-12 Rβ1 extracellular domain, expressed in NSO cells

Application

Anti-interleukin-12 receptor β1 antibody can be used in immunoblotting for localization and detection of recombinant human IL-12 Rβ1.

Physical form

Lyophilized from 0.2 μm filtered solution of phosphate buffered saline