I4023
Interferon from rat kidney cells stimulated with poly (I:C)
lyophilized powder, ≥1 × 105 IRU/mg protein (IRU = International Reference Unit)
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About This Item
MDL number:
UNSPSC Code:
51111800
biological source
rat
description
non-irradiated, sterile filtered
form
lyophilized powder
specific activity
≥1 × 105 IRU/mg protein (IRU = International Reference Unit)
packaging
pkg of 150K U
storage condition
avoid repeated freeze/thaw cycles
UniProt accession no.
storage temp.
2-8°C
Gene Information
rat ... Ifng(25712)
Unit Definition
One unit protects 50% of the indicator cells from viral cytopathology.
Physical form
Lyophilized from 0.4 M glycine HCl, pH 3.5
Analysis Note
Potency: Established in multiple comparative assays with the interferon reference reagents provided by the Antiviral Substances Program, NIAID, NIH, using a modified dye-uptake assay. The protein concentration was established using the Coomassie blue-binding assay with bovine albumin as a standard.
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Peter Hoffmann et al.
Regulatory peptides, 168(1-3), 27-31 (2011-03-10)
Interferon γ (IFNγ) has been originally identified by its anti-viral activity and has been demonstrated to act as potent modulator of the immune system with a range of target cells limited largely to immune cell populations. Although IFNγ has been
Hamid Reza Jafarinaveh et al.
Iranian journal of allergy, asthma, and immunology, 13(2), 125-130 (2013-12-18)
Increased levels of proinflammatory cytokines have been recorded after the onset of transient or permanent brain ischemia and are usually associated with exacerbation of ischemic injury. Embolic stroke model is more relevant to the pathophysiological situation in such patients, because
Finter, N.B.,
The Journal of General Virology, 5, 419-419 (1969)
Ge Hu et al.
Immunopharmacology and immunotoxicology, 32(4), 656-662 (2010-03-11)
Although researchers have recently begun to pay more attention to the immunological characteristics of microvascular endothelial cells (MVECs), there are no reports on whether activation of MVECs by interferon-γ (IFN-γ) exerts any influence on the expressions of IFN-α/β. In the
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.
M M Bradford
Analytical biochemistry, 72, 248-254 (1976-05-07)
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