I0636
Monoclonal Anti-Human IgA antibody produced in mouse
clone GA-112, ascites fluid
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About This Item
MDL number:
UNSPSC Code:
12352203
Recommended Products
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
GA-112, monoclonal
contains
15 mM sodium azide
technique(s)
indirect ELISA: 1:1,000
isotype
IgG1
shipped in
dry ice
storage temp.
−20°C
Specificity
The antibody is specific for the heavy chain of IgA in serum and colostrum. No cross-reactivity with IgG, IgM, IgD, or IgE is observed.
Storage and Stability
For continuous use, store at 2-8 °C, for up to onemonth. For extended storage, solution may be frozen inworking aliquots. Repeated freezing and thawing is notrecommended. Storage in "frost-free" freezers is notrecommended. If slight turbidity occurs upon prolongedstorage, clarify by centrifugation before use.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk_germany
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
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Hui Zheng et al.
Cell biology international, 31(1), 82-87 (2006-11-01)
It is generally believed that under normal conditions only B lymphocytes express immunoglobulin. Interestingly, our previous work demonstrated that epithelial cancer tissues and cancer cell lines also express Ig alpha heavy chain. So we further analyzed the potential function of
M Calvo et al.
The Journal of biological chemistry, 275(11), 7910-7917 (2000-03-14)
The endocytic compartment of polarized cells is organized in basolateral and apical endosomes plus those endocytic structures specialized in recycling and transcytosis, which are still poorly characterized. The complexity of the various populations of endosomes has been demonstrated by the
Hui Zheng et al.
Molecular immunology, 44(9), 2221-2227 (2006-12-19)
Generally, only B lymphocytes express immunoglobulin. Recently, we found the expression of Ig alpha heavy chain in human epithelial cancer cells unexpectedly. We first detected Ig VDJ-Calpha and Ialpha-Calpha transcripts in multiple cancer cell lines. Further, the configuration of the
Duosha Hu et al.
Cellular & molecular immunology, 8(6), 479-485 (2011-08-24)
Accumulating evidence has shown that immunoglobulin (Ig) is 'unexpectedly' expressed by epithelial cancer cells and that it can promote tumor growth. The main purpose of this study was to explore the components of the cancerous Ig and its possible function.
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