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H7259

Sigma-Aldrich

trans-4-Hydroxy-L-proline β-naphthylamide

≥98% (TLC)

Synonym(s):

HydroxyPro-betaNA

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About This Item

Empirical Formula (Hill Notation):
C15H16N2O2
CAS Number:
3326-64-5
Molecular Weight:
256.30
EC Number:
222-045-7
MDL number:
MFCD00083632
UNSPSC Code:
12352209
PubChem Substance ID:
24895789
NACRES:
NA.26

Product Name

trans-4-Hydroxy-L-proline β-naphthylamide,

assay

≥98% (TLC)

form

powder

color

white

application(s)

detection

storage temp.

−20°C

SMILES string

O[C@H]1CN[C@@H](C1)C(=O)Nc2ccc3ccccc3c2

InChI

1S/C15H16N2O2/c18-13-8-14(16-9-13)15(19)17-12-6-5-10-3-1-2-4-11(10)7-12/h1-7,13-14,16,18H,8-9H2,(H,17,19)/t13-,14+/m1/s1

InChI key

RPDYJTXWIGUABB-KGLIPLIRSA-N

Application

Trans-4-Hydroxy-L-proline β-naphthylamide (HydroxyPro-βNA) is used for colorimetric determination of bacterial peptidase(s).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H351

pcodes

P281

Hazard Classifications

Carc. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ8305
BCBJ7539V
1401565V
1398675V
1401565

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Yoshitaka Nakajima et al.
Journal of bacteriology, 188(4), 1599-1606 (2006-02-03)
The prolyl aminopeptidase complexes of Ala-TBODA [2-alanyl-5-tert-butyl-(1, 3, 4)-oxadiazole] and Sar-TBODA [2-sarcosyl-5-tert-butyl-(1, 3, 4)-oxadiazole] were analyzed by X-ray crystallography at 2.4 angstroms resolution. Frames of alanine and sarcosine residues were well superimposed on each other in the pyrrolidine ring of
T Yoshimoto et al.
Journal of biochemistry, 104(4), 622-627 (1988-10-01)
High prolyl endopeptidase (post-proline cleaving enzyme) [EC 3.4.21.26] activity was detected in fruit bodies of shakashimeji (Lyophyllum cinerascens), tsukuritake (mushroom: Agaricus bisporus), hirohachichitake (Lactarius hygrophoroides), and yaburebenitake (Russula lepida) which belong to the genus Basidiomycetes. Cell-free extract of shakashimeji showed
M Gatti et al.
Journal of applied microbiology, 96(2), 223-229 (2004-01-16)
The aim of the present work was to evaluate the enzymatic potential manifested by aminopeptidase activity of different thermophilic Lactobacillus biotypes and to measure the influence of cell growth phase on enzyme expression. The activities were evaluated by the hydrolysis

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