H4511
Serotonin hydrogen maleate
powder
Synonym(s):
3-(2-Aminoethyl)-5-hydroxyindole hydrogen maleate, 5-HT, 5-Hydroxytryptamine hydrogen maleate
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About This Item
Empirical Formula (Hill Notation):
C10H12N2O · C4H4O4
CAS Number:
Molecular Weight:
292.29
Beilstein/REAXYS Number:
8173182
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
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form
powder
color
off-white to yellow
storage temp.
2-8°C
SMILES string
OC(=O)\C=C/C(O)=O.NCCc1c[nH]c2ccc(O)cc12
InChI
1S/C10H12N2O.C4H4O4/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10;5-3(6)1-2-4(7)8/h1-2,5-6,12-13H,3-4,11H2;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key
LTEXAUVYLLADEB-BTJKTKAUSA-N
Gene Information
human ... HTR3A(3359)
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Kerry L Price et al.
ACS chemical neuroscience, 6(7), 1151-1157 (2015-02-05)
Cys-loop receptors are the site of action of many therapeutic drugs. One of these is the smoking cessation agent varenicline, which has its major therapeutic effects at nicotinic acetylcholine (nACh) receptors but also acts at 5-HT3 receptors. Here, we report
Jason Neidleman et al.
Cell reports, 36(3), 109414-109414 (2021-07-15)
Although T cells are likely players in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunity, little is known about the phenotypic features of SARS-CoV-2-specific T cells associated with recovery from severe coronavirus disease 2019 (COVID-19). We analyze T cells from 34 individuals with
Jason Neidleman et al.
Cell reports. Medicine, 1(6), 100081-100081 (2020-08-26)
Convalescing coronavirus disease 2019 (COVID-19) patients mount robust T cell responses against SARS-CoV-2, suggesting an important role of T cells in viral clearance. To date, the phenotypes of SARS-CoV-2-specific T cells remain poorly defined. Using 38-parameter CyTOF, we phenotyped longitudinal specimens of SARS-CoV-2-specific
Di Wang et al.
Journal of neurophysiology, 112(1), 30-38 (2014-04-18)
The lamprey central nervous system has been used extensively as a model system for investigating the networks underlying vertebrate motor behavior. The locomotor networks can be activated by application of glutamate agonists, such as N-methyl-D-aspartic acid (NMDA), to the isolated
Toko Maehara et al.
British journal of pharmacology, 172(4), 1136-1147 (2014-11-08)
Post-operative ileus (POI) is induced by intestinal inflammation. Here, we aimed to clarify the effects of 5-HT3 receptor antagonists against POI. We administered three 5-HT3 receptor antagonists, ondansetron, tropisetron and palonosetron, to a mouse model of POI induced by surgical
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