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Key Documents

H4285

Sigma-Aldrich

HIV-2 env antigen

≥95% (SDS-PAGE), recombinant, expressed in E. coli, Galactosidase-tagged

Synonym(s):

gp36 antigen

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About This Item

MDL number:
UNSPSC Code:
12352200

recombinant

expressed in E. coli

assay

≥95% (SDS-PAGE)

form

solution

mol wt

34 kDa (plus 114 kDa β-Gal tag)

concentration

1 mg/mL

UniProt accession no.

storage temp.

2-8°C

Gene Information

human immunodeficiency virus 2 ... HIV2gp7(1724717)

General description

The gp36 (glycoprotein-36) is a HIV (human immunodeficiency virus)-2 envelope transmembrane glycoprotein. It can be effectively used for the discrimination of HIV-1 and HIV-2.

Biochem/physiol Actions

Positive control for HIV antibodies.

Physical form

Solution in 10 mM Na2CO3, pH 8.0, 10 mM EDTA, 14 mM 2-mercaptoethanol, 0.05% Tween 20.

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M A Rey et al.
Journal of virology, 63(2), 647-658 (1989-02-01)
Four glycoproteins with apparent molecular weights of 300,000, 140,000, 125,000, and 36,000 (gp300, gp140, gp125, and gp36) were detectable in human immunodeficiency virus type 2 (HIV-2)-infected cells. gp125 and gp36 are the external and transmembrane components, respectively, of the envelope
R Kannangai et al.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 22(1), 41-46 (2001-06-22)
HIV-1 and HIV-2 infections differ in prognosis, and may also require different prevention and/or treatment approaches. Thus, estimating the true prevalence of HIV-1 and HIV-2 infections, as well as co-infections, is a critical step in controlling the disease. There are

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