Anti-SSR4 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions
Translocon-associated heterotetrameric protein subunit δ is a protein encoded by the SSR4 gene in humans. It is found to be upregulated in tumors of advanced stages. It acts as a candidate gene with potential functions that might be associated with ultraviolet-induced melanomagenesis and metastasis. Mutation in SSR4 gene causes congenital disorders of glycosylation (CDG).
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
The human ortholog of Monodelphis translocon-associated protein delta subunit gene (TRAPD) was identified as a differentially expressed transcript using the differential display technique, and the two phenotypically distinct opossum melanoma cell lines TD6b and TD15L2 as the tissue resource. The
Human molecular genetics, 23(6), 1602-1605 (2013-11-13)
Nearly 50 congenital disorders of glycosylation (CDG) are known, but many patients biochemically diagnosed with CDG do not have mutations in known genes. Here, we describe a 16-year-old male who was born with microcephaly, developed intellectual disability, gastroesophageal reflux and
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