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GW22818

Sigma-Aldrich

Anti-SEC23B antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

chicken

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

rat, human, mouse

manufacturer/tradename

Genway 15-288-22818

technique(s)

western blot: suitable

NCBI accession no.

NP_116781.1

UniProt accession no.

Q15437

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SEC23B(10483)

Immunogen

Immunogen Sequence: GI # 14591926, sequence 219-530
Recombinant sec23 (S. cerevisiae) homolog B

Application

Anti-SEC23B antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

Protein transport protein Sec23B is a protein encoded by the SEC23B gene in humans. Mutation in this gene is associated with CDAII disease and it also results in a significant decrease of SEC23B transcript in erythroid precursors. Decreased Sec23B protein levels in erythroid precursors is correlated with down-regulation of the SEC23B mRNA transcript.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificates of Analysis (COA)

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Francesca Punzo et al.
Orphanet journal of rare diseases, 6, 89-89 (2012-01-03)
Congenital dyserythropoietic anemia type II (CDAII), the most common form of CDA, is an autosomal recessive condition. CDAII diagnosis is based on invasive, expensive, and time consuming tests that are available only in specialized laboratories. The recent identification of SEC23B

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