Immunogen Sequence: GI # 19718734, sequence 215-410
Recombinant toll-like receptor 2
Application
Anti-TLR2 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions
Toll-like receptor 2 is a protein encoded by the TLR2 gene in humans. It is also referred to as CD282 (cluster of differentiation 282). TLR2 is associated with the pathogenesis of inflammatory and noninflammatory acne lesions. It plays a crutial role in innate immune responses and possesses the ability to recognize as well as sense a wide repertoire of infectious and endogenous cellular structural elements. TLR2 also has a potential role in the pathogen-mediated susceptibility to bipolar disorder (BD).
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Journal of affective disorders, 165, 135-141 (2014-06-03)
Toll-like receptor 2 (TLR2) molecules play a pivotal role in innate immune responses by their ability to recognize and sense a wide repertoire of infectious and endogenous cellular structural elements. Here we evaluated whether genetic variants in TLR2 influence the
Analytical and quantitative cytopathology and histopathology, 36(2), 100-110 (2014-06-07)
To elucidate the role of toll-like receptor 2 (TLR2) in the pathogenesis of acne vulgaris through its immunohistochemical localization in inflammatory and noninflammatory lesions of this disease entity. Using standard immunohistochemical techniques, we examined 30 acne cases (involved and noninvolved
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