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GW22698

Sigma-Aldrich

Anti-CEACAM7 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

chicken

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

manufacturer/tradename

Genway 15-288-22698

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CEACAM7(1087)

Immunogen

Immunogen Sequence: GI # 1082275, sequence 81-97
Synthetic peptide sequence of carcinoembryonic antigen CGM2-human.

Application

Anti-CEACAM7 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

Carcinoembryonic antigen-related cell adhesion molecule 7 is a protein encoded by the CEACAM7 gene in humans and is expressed in normal mucosal epithelia of the colon. Its expression is associated with tumor differentiation as well as with gastric carcinoma. It may act as a useful post-operative predictor for patients with gastric carcinoma.[1] The protein expression is significantly decreased in rectal cancer.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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T Kinugasa et al.
International journal of cancer, 76(1), 148-153 (1998-04-09)
Four human carcinoembryonic antigen (CEA) family members, CEA (CD66e), non-specific cross-reacting antigen (NCA, CD66c), biliary glycoprotein (BGP, CD66a) and CEA gene-family member 2 (CGM2), are expressed in normal mucosal epithelia of the colon. Expression of BGP and CGM2 has recently
Jinfeng Zhou et al.
World journal of surgical oncology, 9, 172-172 (2011-12-27)
The significance of carcinoembryonic antigen-related cell adhesion molecule 7 (CEACAM7) expression in gastric carcinoma and precancerous lesions and its correlation with CEA expression has rarely been previously investigated. CEACAM7 and CEA expression was detected by immunohistochemistry in consecutive sections of
Craig A Messick et al.
Surgery, 147(5), 713-719 (2009-12-17)
The identification of rectal cancer patients predisposed to developing recurrent disease could allow directed adjuvant therapy to improve outcomes while decreasing unnecessary morbidity. This study evaluates carcinoembryonic antigen cellular adhesion molecule-7 (CEACAM-7) expression in rectal cancer as a predictive recurrence

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