GW22572F
Anti-NME1 antibody produced in chicken
affinity isolated antibody, buffered aqueous solution
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
chicken
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... NME1(4830)
General description
NME1 (NME/NM23 nucleoside diphosphate kinase 1) is a member of the NME family of proteins, which in human contains around 10 members.[1] This gene belongs to group I within the NME protein family, and they have nucleotide diphosphate kinase activity. It was initially recognized in highly metastatic cell lines and tumors, as a candidate metastasis suppressor gene.
Immunogen
Immunogen Sequence: GI # 4557797, sequence 1-152
Recombinant non-metastatic cells 1, protein (NM23A) expressed in isoform b
Application
Anti-NME1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions
Nucleoside diphosphate kinase A (NME1) is a wide-spectrum tumor metastasis suppressor gene that plays an important role in suppressing the proliferation, adhesion and invasion of endometrial stromal cells (ESCs). It helps in suppressing the invasion and metastasis of tumor cells. NME1 expression is related with tumour metastatic potential in various human carcinoma, mostly in ductal breast and colorectal carcinomas. It may have a role in gastric carcinoma pathogenesis.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
Not finding the right product?
Try our Product Selector Tool.
recommended
Product No.
Description
Pricing
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Don't see the Right Version?
If you require a particular version, you can look up a specific certificate by the Lot or Batch number.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Nozomi Niitsu
Journal of clinical and experimental hematopathology : JCEH, 54(3), 171-177 (2014-12-17)
nm23-H1 was originally identified as a protein that is expressed at a lower than usual level in metastatic cancer cells. The nm23 genes play critical roles in cellular proliferation, differentiation, oncogenesis, and tumor metastasis. Peripheral T-cell lymphoma (PTCL) is relatively
William A Kanner et al.
The American Journal of dermatopathology, 35(4), 452-457 (2013-05-23)
Melanocytic nevus rests in lymph nodes are a known diagnostic challenge, especially in patients with a history of melanoma. Reticulin and NM23 have been studied in this context. The pattern of reticulin staining in melanomas surrounds groups/nests of melanocytes but
Ming-Qing Li et al.
Human reproduction (Oxford, England), 28(10), 2822-2831 (2013-07-17)
Is Nometastatic gene 23-H1 (NME1, also known as nm23-H1) involved in regulating the biological behavior of endometrial stromal cells (ESCs), and does it participate in the pathogenesis of endometriosis? NME1 suppression induces ESC dysfunction in the endometriotic milieu. NME1 is
Kai-Kai Chang et al.
International journal of clinical and experimental pathology, 6(10), 2030-2038 (2013-10-18)
Nonmetastatic gene 23-H1 (NME1, also known as nm23-H1) is a wide-spectrum tumor metastasis suppressor gene that plays an important role in suppressing the proliferation, adhesion and invasion of endometrial stromal cells (ESCs). The present study is undertaken to explore the
Svjetlana Radović et al.
Bosnian journal of basic medical sciences, 13(2), 72-77 (2013-06-04)
NM 23 protein was originally identified as a metastasis suppressor protein. The expression of NM23 has been correlated with tumour metastatic potential in various human carcinoma, mostly in ductal breast and colorectal carcinomas. Evidence for their expression in gastric cancer
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
