GW22331B

Anti-KAT (ab2) antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: chicken
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: rat, human, mouse
• manufacturer/tradename: Genway 15-288-22331B
• technique(s): western blot: suitable
• NCBI accession no.: NP_005877.1
• UniProt accession no.: Q59G59
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... KAT(10300)

Description

General description

KATNB1 (katanin p80 subunit B 1) forms the regulatory component of katanin protein, which also contains the catalytic p60 subunit. This protein is composed of procon80 domain at its C-terminal, and a WD40 domain at its N-terminal. This gene is highly conserved in humans, spans ~1.6kb, and is composed of four exons. It codes for a protein of 115 amino acids, with a molecular weight of 12.5kDa. It has a wide range of tissue expression such as, thymus, heart, lung, liver, kidney, spleen, colon, skeletal muscle and placenta.

Immunogen

Immunogen Sequence: GI # 5031817, sequence 301-511

Recombinant katanin p80 subunit B 1

Application

Anti-KAT (ab2) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

The KAT (thiosulfate sulfurtransferase (rhodanese)-like domain containing 1) protein is found around the nuclear membranes and is expressed in several breast, colon and lung carcinoma cell lines, but not in normal breast epithelial cell lines. It is also detected in invasive ductal carcinoma, but not in adjacent tissues and has a role in tumorigenesis.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)