Immunogen Sequence: GI # 4759152, sequence 206-335
Recombinant spermine synthase; SpS
Application
Anti-SMS antibody produced in chicken is suitable for western blotting at a working dilution of 1:500 and for cell staining at a working dilution of 1:200.
Biochem/physiol Actions
SMS (spermine synthase) encodes a member of the spermidine/spermin synthase family. It catalyzes the synthesis of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM). Defects in this gene are linked to X-linked Snyder-Robinson mental retardation syndrome.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
European journal of human genetics : EJHG, 11(12), 937-944 (2003-09-26)
Polyamines (putrescine, spermidine, spermine) are ubiquitous, simple molecules that interact with a variety of other molecules in the cell, including nucleic acids, phospholipids and proteins. Various studies indicate that polyamines are essential for normal cell growth and differentiation. Furthermore, these
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