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ligand
quaternary amine
description
Ion Exchanger Type (value)
packaging
pkg of 1 ea
manufacturer/tradename
Cytiva 28-9269-78
parameter
44 psi
bed size
7.7 mm × 100 mm
bed volume
4.7 mL
column I.D.
7.7 mm
matrix
highly cross-linked agarose with dextran surface extender
average diameter
90 μm (d50v)
cleaning
2-14
working range
2-12
suitability
suitable for bioprocess medium
Related Categories
General description
HiScreen Capto Q is a column packed with a strong anion exchange modern resin, combining speed and capacity. Suitable for process development. The small column volume of 4.7 mL and bed height of 10 cm make HiScreen columns excellent tools for method optimization, parameter screening, robustness testing, and convenient scale-up. Process fluid velocities can be applied, because the 10 cm bed height provides sufficient residence time. The results can then serve as a basis for linear process scale-up.
Cytiva′s resin couples a quaternary ammonium (Q) strong anion exchanger to a chemically modified, high-flow agarose matrix. The rigid agarose matrix provides greater particle rigidity without compromising pore size, which allows for high bed volume and purification of viscous samples at high flow rates.High dynamic binding capacity is achieved with a dextran surface extender that coats the agarose matrix. The resin’s high binding-capacity, high flow rate, and low back pressure reduce process cycle times and improve productivity at process scale.
Cytiva′s resin couples a quaternary ammonium (Q) strong anion exchanger to a chemically modified, high-flow agarose matrix. The rigid agarose matrix provides greater particle rigidity without compromising pore size, which allows for high bed volume and purification of viscous samples at high flow rates.High dynamic binding capacity is achieved with a dextran surface extender that coats the agarose matrix. The resin’s high binding-capacity, high flow rate, and low back pressure reduce process cycle times and improve productivity at process scale.
Features and Benefits
- Prepacked with Capto Q strong anion exchange chromatography resin.
- Convenient method optimization and parameter screening because of the 10cm bed height.
- These columns are easily connected in series to increase bed height to 20 cm.
- Fast results and minimal consumption of sample and buffer consumption through the small bed volume.
- BioProcess columns packed with the same chromatography resin and using the same linear fluid velocity can produce scalable, reproducible results.
Storage and Stability
Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Store at 4 to 30 °C (20% Ethanol)
Analysis Note
To view the Certificate of Analysis for this product, please visit www.cytiva.com.
Legal Information
Capto is a trademark of Cytiva
HiScreen is a trademark of Cytiva
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