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G8887

Sigma-Aldrich

Glucokinase from Bacillus stearothermophilus

lyophilized powder, ≥250 units/mg protein

Synonym(s):

ATP:D-glucose-6-phosphotransferase

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About This Item

CAS Number:
Enzyme Commission number:
MDL number:
UNSPSC Code:
12352204

biological source

Bacillus sp. (B. stearothermophilus)

Quality Level

form

lyophilized powder

specific activity

≥250 units/mg protein

composition

Protein, ≥60% biuret

shipped in

dry ice

storage temp.

−20°C

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Unit Definition

One unit will phosphorylate 1.0 μmole of D-glucose to D-glucose 6-phosphate per min at pH 9.0 at 30 °C.

Physical form

Lyophilized powder containing Tris buffer salts

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Päivi J Miettinen et al.
Duodecim; laaketieteellinen aikakauskirja, 128(19), 1989-1998 (2012-11-20)
MODY (Maturity-Onset Diabetes of the Young) is a group of monogenic disorders characterized by autosomally dominantly inherited diabetes or hyperglycemia typically detected during adolescence or young adulthood. Usually there is at least one person in the family having developed the
Response to Comment on: Chakera et al. Antenatal diagnosis of fetal genotype determines if maternal hyperglycemia due to a glucokinase mutation requires treatment. Diabetes Care 2012;35:1832-1834.
Ali J Chakera et al.
Diabetes care, 36(1), e15-e15 (2012-12-25)
Comment on: Chakera et al. Antenatal diagnosis of fetal genotype determines if maternal hyperglycemia due to a glucokinase mutation requires treatment. Diabetes Care 2012;35:1832-1834.
Edoardo Tartaglia et al.
Diabetes care, 36(1), e14-e14 (2012-12-25)
Matthew D Blankschien et al.
ACS nano, 7(1), 654-663 (2012-12-15)
The use of plasmonic nanoparticle complexes for biomedical applications such as imaging, gene therapy, and cancer treatment is a rapidly emerging field expected to significantly improve conventional medical practices. In contrast, the use of these types of nanoparticles to noninvasively
David Callejas et al.
Diabetes, 62(5), 1718-1729 (2013-02-05)
Diabetes is associated with severe secondary complications, largely caused by poor glycemic control. Treatment with exogenous insulin fails to prevent these complications completely, leading to significant morbidity and mortality. We previously demonstrated that it is possible to generate a "glucose

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