Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

G4256

Sigma-Aldrich

Galactose-1-phosphate Uridyltransferase from galactose-adapted yeast

Type IV, lyophilized powder, 20-60 units/mg protein (modified Warburg-Christian)

Synonym(s):

GALT, UDP glucose:α-D-galactose-1-phosphate uridyltransferase

Sign Into View Organizational & Contract Pricing

Select a Size

20 UNITS
$964.00
50 UNITS
$1,920.00

$964.00

Available to ship onMay 01, 2025Details

Diagnostics Manufacturers should use alternative grade product: SRE0008
Request a Bulk Order
All Photos(1)

Select a Size

Change View
20 UNITS
$964.00
50 UNITS
$1,920.00

About This Item

CAS Number:
9016-11-9
Enzyme Commission number:
2.7.7.12 (BRENDA, IUBMB)
MDL number:
MFCD00131120
UNSPSC Code:
12352204
NACRES:
NA.54

$964.00

Available to ship onMay 01, 2025Details

Diagnostics Manufacturers should use alternative grade product: SRE0008
Request a Bulk Order

type

Type IV

Quality Level

300

form

lyophilized powder

specific activity

20-60 units/mg protein (modified Warburg-Christian)

composition

Protein, 15-35%

foreign activity

6-phosphogluconate dehydrogenase ≤0.5%
UDP glucose pyrophosphorylase and galactokinase ≤0.2%

storage temp.

−20°C

Looking for similar products? Visit Product Comparison Guide

General description

Research area: Cell Signaling

Galactose-1-phosphate uridyltransferase (GALT) is a galactose metabolizing enzyme that facilitates the simultaneous conversion of uridine diphosphoglucose (UDP-glucose) and galactose-1-phosphate (gal-1P) to uridine diphosphogalactose (UDP-galactose) and glucose-1-phosphate. Classic Galactosemia (CG) is an inherited metabolic condition caused by deficiency of GALT activity.[1] GALT gene is mapped to human chromosome 9p13.[2] Deficiency of GALT results in type 1 galactosemia.[1]

Application

Galactose-1-phosphate Uridyltransferase from galactose-adapted yeast has been used to perform enzyme assays.

Unit Definition

One unit will form 1.0 μmole of glucose 1-phosphate from UDP-glucose, galactose 1-phosphate and NADP+ per min at pH 8.7 at 25 °C as detected by a coupled system using phosphoglucomutase.

Physical form

Contains buffer salts as citrate and reduced glutathione

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000430615
0000430616
0000430616
0000430615
0000328731

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

D-(+)-Galactose ≥99% (HPLC)

Sigma-Aldrich

G0750

D-(+)-Galactose

Neonatal screening, clinical features and genetic testing for galactosemia.
Marco Zaffanello et al.
Genetics in medicine : official journal of the American College of Medical Genetics, 7(3), 211-212 (2005-03-19)
Nir Dai et al.
Plant physiology, 142(1), 294-304 (2006-07-11)
The Cucurbitaceae translocate a significant portion of their photosynthate as raffinose and stachyose, which are galactosyl derivatives of sucrose. These are initially hydrolyzed by alpha-galactosidase to yield free galactose (Gal) and, accordingly, Gal metabolism is an important pathway in Cucurbitaceae
Deborah S Barbouth et al.
Pediatric research, 62(6), 720-724 (2007-10-25)
Classic galactosemia is caused by impaired galactose-1-phosphate uridyltransferase (GALT EC 2.7.712). If discovered and treated within the first days of life, the acute problems of hepatocellular damage, sepsis, and death are prevented. However, chronic problems such as ataxia, tremor, dyspraxic
Jane Odhiambo Mumma et al.
Molecular genetics and metabolism, 93(2), 160-171 (2007-11-06)
Galactose is metabolized in humans and other species by the three-enzyme Leloir pathway comprised of galactokinase (GALK), galactose 1-P uridylyltransferase (GALT), and UDP-galactose 4'-epimerase (GALE). Impairment of GALT or GALE in humans results in the potentially lethal disorder galactosemia, and
Galactose 1-phosphate uridylyltransferase. Isolation of a uridylyl-enzyme intermediate.
L J Wong et al.
The Journal of biological chemistry, 249(7), 2322-2324 (1974-04-10)
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service