G2670

Anti-G Protein-Coupled Receptor AGR9 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-GPCR AR9
• MDL number: MFCD06798454
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 3 μg/mL using human adrenal tissue
• UniProt accession no.: Q8TDS5
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... OXER1(165140)

Description

General description

AGR9 encodes a 483 amino acid protein with seven stretches of hydrophobic amino acids, which represents a G protein-coupled receptor. It is expressed in the cardiovascular, central nervous and digestive systems.

Immunogen

synthetic peptide corresponding to the C-terminal domain of human G protein-coupled receptor AGR9, conjugated to KLH. The immunizing peptide has 100% identity with the mouse gene.

Application

Anti-G Protein-Coupled Receptor AGR9 antibody produced in rabbit is suitable for immunohistochemistry at a working concentration of 3μg/mL using formalin-fixed, paraffin-embedded sections human adrenal tissue.

Biochem/physiol Actions

AGR9 exhibits rhodopsin-like receptor activity. Dibutyryl cyclic AMP and the β-adrenergic agonist isoproterenol, mimic the effect of forskolin. Forskolin causes a marked and transient decrease in the steady-state level of AGR9 mRNA.

Physical form

Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable