G11500-HH

DMT-dG(dmf) Phosphoramidite

• Synonym(s): DMT-dG(dmf) Amidite, N-[(dimethylamino)methylene]-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyguanosine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite], N2-Dimethylformamidine-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]
• Empirical Formula (Hill Notation): C₄₃H₅₃N₈O₇P
• CAS Number: 330628-04-1
• Molecular Weight: 824.90
• MDL number: MFCD00797420
• UNSPSC Code: 12352200
• PubChem Substance ID: 329799821

Properties

• type: for DNA synthesis
• product line: Proligo Reagents
• assay: ≥99% (³¹P-NMR); ≥99.0% (reversed phase HPLC)
• form: powder
• packaging: pkg of 6 × 10 g (G115021-06); pkg of 1 × 100 g (G115011-C02-01); pkg of 6 × 20 g (G115020-06)
• technique(s): oligo synthesis: suitable
• color: white to off-white
• λ: conforms (UV/VIS Identity)
• nucleoside profile: base: guanosine; base protecting group: DMF; 5' protecting group: DMT; deprotection: fast
• storage temp.: −20°C
• SMILES string: COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4C(=O)NC(\N=C/N(C)C)=Nc34)(c5ccccc5)c6ccc(OC)cc6
• InChI: 1S/C43H53N8O7P/c1-29(2)51(30(3)4)59(56-24-12-23-44)58-36-25-38(50-28-45-39-40(50)47-42(48-41(39)52)46-27-49(5)6)57-37(36)26-55-43(31-13-10-9-11-14-31,32-15-19-34(53-7)20-16-32)33-17-21-35(54-8)22-18-33/h9-11,13-22,27-30,36-38H,12,24-26H2,1-8H3,(H,47,48,52)/b46-27-/t36-,37+,38+,59?/m0/s1
• InChI key: YRQAXTCBMPFGAN-UJASEYITSA-N

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable