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G0503

Sigma-Aldrich

Karaya gum

Synonym(s):

Gum karaya from sterculia tree, Tragacanth Indian

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.25
Pricing and availability is not currently available.

biological source

plant fluids (Gum karaya)

Quality Level

form

powder

color

faint yellow to brown

storage temp.

room temp

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Application

Karaya gum may be used for the development of gastro intestinal tract drug delivery vehicles, mucoadhesive sustained release drug delivery and noneffervescent floating drug delivery systems in combination with alginate.[1][2]

Other Notes

Believed to be a partially acetylated polymer of galactose, rhamnose, and glucuronic acid with a M.W. of approx. 9,500,000.
To gain a comprehensive understanding of our extensive range of Oligosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Baljit Singh et al.
International journal of biological macromolecules, 43(2), 142-150 (2008-05-27)
The present paper deals with the modification of the sterculia gum with methacrylic acid (MAAc) to hydrogels for use in drug delivery. The hydrogels were characterized by SEMs, FTIR and swelling studies. The release dynamics of model anti-ulcer drug (ranitidine
Anil Getyala et al.
Current drug delivery, 10(5), 620-629 (2013-01-05)
The aim of the work is to modify the solubility and bioavailability of Losartan potassium, by employing noneffervescent floating drug delivery (tablet dosage forms). Non-effervescent systems are a type of floating drug delivery systems, that have been used to boost
G V Murali Mohan Babu et al.
Drug development and industrial pharmacy, 29(8), 855-864 (2003-10-23)
Solid mixtures of nimesulide (NS) and modified gum karaya (MGK) were prepared to improve the dissolution rate of NS. The effect of drug-carrier ratio on dissolution rate of NS was investigated by preparing the solid mixtures of different ratios by
Amit Ashok Chivate et al.
AAPS PharmSciTech, 9(1), 197-204 (2008-05-01)
The purpose of the research was to evaluate Sterculia foetida gum as a hydrophilic matrix polymer for controlled release preparation. For evaluation as a matrix polymer; characterization of Sterculia foetida gum was done. Viscosity, pH, scanning electronmicrographs were determined. Different
Mysheika LeMaile-Williams et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 43(9), e83-e88 (2006-10-10)
We investigated an outbreak involving 2 patients hospitalized at hospital A with cutaneous Rhizopus arrhizus (oryzae) infections of surgically created stomas. A cohort study involving all patients having ileostomy or colostomy surgery during the outbreak period (January-April 2005) was performed.

Questions

1–2 of 2 Questions  
  1. Whether Karaya Gum is obtained from tamarind seed polysaccharide ? If yes, any other seed polysaccharides also available, like amla seed, soap nut seed, basil seed etc.,

    1 answer
    1. No, this product is from the eponymously named plant, the Gum Karaya tree, not from any part of the Tamarind tree.

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  2. Dear Madam or Sir Is the Karaya gum suitable for food or for oral intake? Is it suitable for use in drugs or as a food supplement? Thank you!

    1 answer
    1. This product is intended for research use only and not suitable for food or oral intake. The item is not suitable for any other purpose which includes, but is not limited to, unauthorized commercial use, in vitro diagnostic use, or therapeutic use in humans or animals.

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