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Key Documents

G0421

Sigma-Aldrich

Poly-L-glutamic acid sodium salt

mol wt >50,000

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352200

form

powder

mol wt

>50,000

color

white to light yellow

storage temp.

−20°C

InChI

1S/C15H23N3O10/c16-7(1-4-10(19)20)13(25)17-8(2-5-11(21)22)14(26)18-9(15(27)28)3-6-12(23)24/h7-9H,1-6,16H2,(H,17,25)(H,18,26)(H,19,20)(H,21,22)(H,23,24)(H,27,28)/t7-,8-,9-/m0/s1

InChI key

BUZMZDDKFCSKOT-CIUDSAMLSA-N

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Biochem/physiol Actions

Poly-L-glutamic acid is an anionic biocompatible polymer used in combination with cationic biopolymers such as poly-lysine to form stable time-release controlled polyelectrolyte shells to protect drug and molecular delivery structures such as protein-loaded starch microgels and nanocapsules.

Analysis Note

Molecular weight based on viscosity.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Alfonso P Farruggio et al.
Biology open, 3(10), 895-903 (2014-09-14)
In recent years, application of serine integrases for genomic engineering has increased in popularity. The factor-independence and unidirectionality of these large serine recombinases makes them well suited for reactions such as site-directed vector integration and cassette exchange in a wide
Yuan Li et al.
Langmuir : the ACS journal of surfaces and colloids, 28(2), 1545-1551 (2011-12-14)
The interaction of biocompatible polyelectrolytes (chargeable poly(amino acids)) with oxidized starch microgel particles has been studied. The aim was to form a polyelectrolyte complex layer around the outer shell of microgel particles filled with functional ingredients to slow down the
Alexei A Antipov et al.
Advances in colloid and interface science, 111(1-2), 49-61 (2004-12-02)
This review is devoted to a novel type of polymer micro- and nanocapsules. The shell of the capsule is fabricated by alternate adsorption of oppositely charged polyelectrolytes (PEs) onto the surface of colloidal particles. Cores of different nature (organic or
Bruno G De Geest et al.
Chemical Society reviews, 36(4), 636-649 (2007-03-28)
Polyelectrolyte capsules have recently been introduced as new microscopic vehicles which could have high potential in the biomedical field. In this critical review we give an introduction to the layer-by-layer (LbL) technique which is used to fabricate these polyelectrolyte capsules
K Szczepanowicz et al.
Langmuir : the ACS journal of surfaces and colloids, 26(15), 12592-12597 (2010-07-08)
The aim of this work was to develop a novel method of preparation of loaded nanosize capsules based on liquid core encapsulation by biocompatible polyelectrolyte (PE) multilayer adsorption, with or without pegylated outermost layer. Using AOT (docusate sodium salt) as

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