F8549

Fluprostenol

10 mg/mL in ethanol, 98%

• Synonym(s): (±)-16-(3-Trifluoromethylphenoxy)tetranorprostaglandin F_2α
• Empirical Formula (Hill Notation): C₂₃H₂₉F₃O₆
• CAS Number: 40666-16-8
• Molecular Weight: 458.47
• EC Number: 200-578-6
• MDL number: MFCD03427566
• UNSPSC Code: 12352202
• PubChem Substance ID: 24894969
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: 98%
• concentration: 10 mg/mL in ethanol
• storage temp.: −20°C
• SMILES string: O[C@H](COc1cccc(c1)C(F)(F)F)\C=C\[C@@H]2[C@@H](O)C[C@@H](O)[C@H]2C\C=C/CCCC(O)=O
• InChI: 1S/C23H29F3O6/c24-23(25,26)15-6-5-7-17(12-15)32-14-16(27)10-11-19-18(20(28)13-21(19)29)8-3-1-2-4-9-22(30)31/h1,3,5-7,10-12,16,18-21,27-29H,2,4,8-9,13-14H2,(H,30,31)/b3-1-,11-10+/t16-,18-,19-,20+,21-/m0/s1
• InChI key: WWSWYXNVCBLWNZ-CHPNCWRZSA-N

Description

Application

Fluprostenol has been used as a prostaglandin F (FP) receptor agonist to study its effects on osteoclast development. It has also been used as a prostaglandin F2α (PGF2α) receptor agonist to study its effects on mitogen-activated protein kinase (MAPK) signaling in rat aorta.

Biochem/physiol Actions

Fluprostenol is a selective prostaglandin F2-α (PGF2α) receptor or prostaglandin F (FP) receptor agonist.

Safety Information

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H319
• pcodes: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter