F7776

Monoclonal Anti-MAP Kinase, Activated (Diphosphorylated ERK-1&2)−FITC antibody produced in mouse

clone MAPK-YT, purified immunoglobulin, buffered aqueous solution

• Synonym(s): Monoclonal Anti-MAP Kinase, Activated (Diphosphorylated ERK-1&2)
• UNSPSC Code: 12352203

Properties

• biological source: mouse
• conjugate: FITC conjugate
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: MAPK-YT, monoclonal
• form: buffered aqueous solution
• mol wt: antigen ERK-1 44 kDa; antigen ERK-2 42 kDa
• species reactivity: human, Caenorhabditis elegans, Xenopus, Drosophila, hamster, rat, bovine, mouse, yeast
• technique(s): direct immunofluorescence: 1:20 using cultured human foreskin fibroblasts (paraformaldehyde-fixation)
• isotype: IgG1
• UniProt accession no.: P28482
• shipped in: dry ice
• Storage temp.: −20°C
• Gene Information: human ... MAPK1(5594) , MAPK3(5595) ; mouse ... Mapk1(26413) , Mapk3(26417) ; rat ... Mapk1(116590) , Mapk3(50689)

Description

Specificity

The antibody reacts specifically with the diphosphorylated form of MAP kinase (ERK-1 and ERK-2). It does not recognize the non-phosphorylated or the monophosphorylated forms of MAP kinase or the diphosphorylated forms of JNK and p38 MAP kinase. The epitope recognized by the antibody contains the phosphorylated threonine and tyrosine residues within the regulatory site of active MAP kinase.

Immunogen

synthetic peptide HTGFLpTEpYVAT corresponding to the phosphorylated form of the ERK-activation loop.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)