Skip to Content
MilliporeSigma
All Photos(3)

Key Documents

View All Documentation

F6680

Sigma-Aldrich

Anti-FGR (28-40) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):

Anti-SRC2, Anti-cfgr, Anti-csrc2, Anti-p55cfgr, Anti-p58cfgr, Anti-proto-oncogene tyrosine-protein kinase FGR (Homo sapiens)

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

UNSPSC Code:
12352203

biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~59 kDa

species reactivity

human

technique(s)

western blot: 1:500-1:2,000

UniProt accession no.

P09769

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... FGR(2268)

Immunogen

synthetic peptide corresponding to amino acids 28-40 of human FGR.

Application

Anti-FGR (28-40) antibody is suitable for western blot at a dilution of 1:500-1:2,000.
Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about us and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

Biochem/physiol Actions

FGR belongs to SRC family of protein tyrosine kinases (PTKs). It is highly expressed in lymph nodes and partially in spleen and peripheral blood leukocytes. It was barely in the thymus and was not detected in bone marrow. It plays an important role in transmitting signals from cell surface receptors devoid of kinase activity and contributes to the regulation of immune responses. It is also associated with neutrophil, monocyte, macrophage mast cell functions and cytoskeleton remodeling in response to extracellular stimuli, phagocytosis, cell adhesion and migration.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
019K2702

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

O Sartor et al.
The Journal of biological chemistry, 267(5), 3460-3465 (1992-02-15)
The c-fgr proto-oncogene specifies a nonreceptor protein-tyrosine kinase, p55c-fgr, a member of the src family. In the present study, we have mutagenized c-fgr to mimic alterations found at the 3' end of the v-fgr oncogene and have investigated the biologic
S Hatakeyama et al.
Proceedings of the National Academy of Sciences of the United States of America, 91(8), 3458-3462 (1994-04-12)
The c-fgr gene is a member of the Src family of protooncogene tyrosine kinases. A monoclonal antibody (2H2) that recognizes the specific region of the N-terminal domain of the murine c-fgr gene product (Fgr) has been established. With an immune
M Patel et al.
Pathobiology : journal of immunopathology, molecular and cellular biology, 59(4), 289-292 (1991-01-01)
The c-fgr proto-oncogene, which is a member of the c-src gene family, encodes the cytoplasmic tyrosine kinase p55c-fgr. Expression of the c-fgr gene is activated in human B lymphocytes following infection with Epstein-Barr virus, and the viral protein EBNA-2 is
G Berton et al.
The Journal of cell biology, 126(4), 1111-1121 (1994-08-01)
Stimulation of adherent human neutrophils (PMN) with tumor necrosis factor (TNF) triggers protein tyrosine phosphorylation (Fuortes, M., W. W. Jin, and C. Nathan. 1993. J. Cell Biol. 120:777-784). We investigated the dependence of this response on beta 2 integrins by

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service