F3179

Anti-Frizzled-3 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-FZD3
• MDL number: MFCD06798445
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human
• availability: not available in Japan
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 5 μg/mL using human skeletal muscle
• UniProt accession no.: Q9NPG1
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... FZD3(7976) ; mouse ... Fzd3(14365) ; rat ... Fzd3(266715)

Description

General description

FZD3 belongs to the frizzled (Fz) family. Frizzled homolog protein (FZD) is a seven-pass transmembrane type receptor expressed in various normal tissues (skeletal muscle, kidney, pancreas, cerebellum and cerebral cortex). In human, ten members (FZD1-FZD10) of Frizzled homolog protein have been identified. It is expressed in several cancers (esophageal carcinoma, lung squamous cell carcinoma, primary acute and lymphoblastic leukemia, myeloma, lymphoma and Ewing sarcoma).[1]

Immunogen

synthetic peptide corresponding to the N-terminal extracellular domain of human frizzled-3, conjugated to KLH. The immunizing peptide has 100% homology with the rat and mouse gene.

Application

Anti-Frizzled-3 antibody is suitable for western blot analysis. It is also suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections) at a concentration of 5μg/mL, using human skeletal muscle.

Physical form

Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.