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EMU088201

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Cdc25a

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GGGAAGCATCAGGATTTGAAATATATTTCTCCAGAAATTATGGCATCTGTTTTGAATGGCAAGTTTGCCAGTCTCATTAAAGAGTTTGTTATCATTGACTGCCGATACCCATATGAGTATGAAGGAGGTCACATCAAGGGTGCCGTGAATCTGCACATGGAAGAAGAGGTTGAAGACTTCTTACTTAAGAACCCTATTGTGCCTACTGATGGCAAGCGTGTCATTGTCGTGTTCCACTGTGAGTTTTCCTCTGAAAGAGGCCCTCGAATGTGCCGATATGTGAGAGAGAGAGATAGGCTCGGCAATGAGTACCCCAAGCTCCACTACCCTGAGCTGTATGTCCTGAAAGGGGGATACAAGGAGTTCTTTTTGAAGTGCCAGTCTCACTGTGAACCCCCCAGCTACCGGCCAATGCACCATGAAGACTTTAAAGAAGACCTAAAGAAGTTCCGCACCAAGAGCCGGACCTGGGCAGGAGAAAAGAGGAAAAGAGAGATGTACAGTCGCCTGAAGAAGCTCTGAAGCCAAATGG

Ensembl | mouse accession no.

ENSMUSG00000032477

NCBI accession no.

NM_007658

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... CDC25A(12530) , Cdc25a(12530)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Sarah Bertoli et al.
Oncotarget, 6(35), 38061-38078 (2015-10-31)
We investigated cell cycle regulation in acute myeloid leukemia cells expressing the FLT3-ITD mutated tyrosine kinase receptor, an underexplored field in this disease. Upon FLT3 inhibition, CDC25A mRNA and protein were rapidly down-regulated, while levels of other cell cycle proteins

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