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EMU023001

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Irf8

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20 μG
$220.00
50 μG
$391.00

$220.00

Usually ships in 3 weeks (4 to 6 weeks for custom orders).
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20 μG
$220.00
50 μG
$391.00

About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

$220.00

Usually ships in 3 weeks (4 to 6 weeks for custom orders).

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GATCGAACAGATCGACAGCAGCATGTACCCGGGGCTGATCTGGGAAAATGATGAGAAGACCATGTTCCGTATCCCCTGGAAGCATGCCGGCAAGCAGGATTACAATCAGGAGGTGGATGCTTCCATCTTCAAGGCCTGGGCAGTTTTTAAAGGGAAGTTTAAAGAGGGAGACAAAGCTGAACCAGCCACGTGGAAGACGAGGTTACGCTGTGCTCTGAACAAGAGCCCAGATTTTGAAGAAGTGACTGACCGGTCCCAGCTGGACATTTCTGAGCCATATAAAGTTTACCGAATTGTCCCCGAGGAAGAACAAAAATGCAAGCTGGGCGTGGCACCTGCAGGCTGCATGAGCGAAGTTCCTGAGATGGAGTGTGGCCGCTCAGAGATTGAGGAGCTGATCAAGGAACCTTCTGTGGATGAGTACATGGGTATGACCAAGAGGAGCCCA

Ensembl | mouse accession no.

ENSMUSG00000041515

NCBI accession no.

NM_008320

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... IRF8(15900) , Irf8(15900)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

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XWR
AOR

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Ji-Ye Kee et al.
BMC cancer, 14, 949-949 (2014-12-17)
Inhibition of metastasis through upregulation of immune surveillance is a major purpose of chemokine gene therapy. In this study, we focused on a membrane-bound chemokine CXCL16, which has shown a correlation with a good prognosis for colorectal cancer (CRC) patients.
Chunyuan Guo et al.
Kidney international, 92(5), 1194-1205 (2017-07-16)
DNA methylation is an epigenetic mechanism that regulates gene transcription without changing primary nucleotide sequences. In mammals, DNA methylation involves the covalent addition of a methyl group to the 5-carbon position of cytosine by DNA methyltransferases (DNMTs). The change of
Takuya Yashiro et al.
Scientific reports, 9(1), 1161-1161 (2019-02-06)
The chemokine CCL22 is predominantly produced by dendritic cells (DCs) and macrophages. CCL22 acts on CCR4-expressing cells including Th2 and Treg. Although a correlation between the CCL22-CCR4 axis and allergic diseases has been established, the mechanism of monocyte lineage-specific Ccl22
Makoto Horiuchi et al.
Journal of neuroinflammation, 8, 8-8 (2011-01-26)
Administration of exogenous interferon-γ (IFNγ) aggravates the symptoms of multiple sclerosis (MS), whereas interferon-β (IFNβ) is used for treatment of MS patients. We previously demonstrated that IFNγ induces apoptosis of oligodendroglial progenitor cells (OPCs), suggesting that IFNγ is more toxic

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