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EMU004631

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Obfc2b

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CAGTGAGCCCAATCCAGAGTATAACACGCAGCAGGCGCCCAACAAATCGGTGCAGAACAATGACAACAGCCCTACTGCCCCACAAGCGACCACGGGACCCCCTGCTGCCTCTCCAGCTTCCGAGAACCAGAACGGAAATGGACTGAGCACCCAGCTAGGTCCTGTGGGTGGCCCCCATCCTTCTCACACCCCCTCACATCCCCCCAGCACCCGAATCACTCGAAGTCAACCCAACCACACGCCTTCCGGCCCTCCTGGCCCCTCCAGCAACCCTGTCAGCAACGGCAAAGAAACCCGAAGAAGCAGCAAGAGATAGCAAGAGATGAGTCTCTCCTTCCTTCCACCACAACCATGATCCAGGCGTCTCTGCCAGAGAACAAGACAGTCTTCTATCAGGCTGCTGGCTT

Ensembl | mouse accession no.

ENSMUSG00000025374

NCBI accession no.

NM_027257

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... OBFC2B(69917) , Obfc2b(69917)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Nicolas Paquet et al.
Scientific reports, 6, 27446-27446 (2016-06-09)
The maintenance of genome stability is an essential cellular process to prevent the development of diseases including cancer. hSSB1 (NABP2/ OBFC2A) is a critical component of the DNA damage response where it participates in the repair of double-strand DNA breaks
Emma Bolderson et al.
Nucleic acids research, 42(10), 6326-6336 (2014-04-23)
Aberrant DNA replication is a primary cause of mutations that are associated with pathological disorders including cancer. During DNA metabolism, the primary causes of replication fork stalling include secondary DNA structures, highly transcribed regions and damaged DNA. The restart of

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