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Key Documents

COO/COA

EHU070761

MISSION^® esiRNA

Name: MISSION<SUP>®</SUP> esiRNA
Brand: SIGMA

targeting human MINA

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About This Item

UNSPSC Code:

41105324

NACRES:

NA.51

description

product line

MISSION^®

form

lyophilized powder

esiRNA cDNA target sequence

GATGCCAAAGAAAGCAAAGCCTACAGGGAGTGGGAAGGAAGAGGGGCCGGCTCCCTGTAAGCAGATGAAGTTAGAAGCAGCTGGGGGGCCTTCAGCTTTAAACTTTGACAGTCCCAGTAGTCTCTTTGAAAGTTTAATCTCGCCCATCAAGACAGAGACTTTTTTCAAGGAATTCTGGGAGCAGAAGCCCCTTCTCATTCAGAGAGATGACCCTGCACTGGCCACATACTATGGGTCCCTGTTCAAGCTAACAGATCTGAAGAGTCTGTGCAGCCGGGGGATGTACTATGGAAGAGATGTGAATGTCTGCCGGTGTGTCAATGGGAAGAAGAAGGTTTTAAATAAAGATGGCAAAGCACACTTTCTTCAGCTGAGAAAAGATTTTGATCAGAAAAGGGCAACGATTCAGTTTCACCAACCTCAGAGATTTAAGGATGAGCTTTGGAGGATCCA

Ensembl | human accession no.

ENSG00000170854

NCBI accession no.

NM_032778

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... MINA(84864) , MINA(131544)

Related Categories

MISSION® esiRNA

Oligos, qPCR Probes & Peptides

General description

MISSION^® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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A CRISPR/Cas9 screen identifies the histone demethylase MINA53 as a novel HIV-1 latency-promoting gene (LPG).

Huachao Huang et al.

Nucleic acids research, 47(14), 7333-7347 (2019-06-06)

Although combination antiretroviral therapy is potent to block active replication of HIV-1 in AIDS patients, HIV-1 persists as transcriptionally inactive proviruses in infected cells. These HIV-1 latent reservoirs remain a major obstacle for clearance of HIV-1. Investigation of host factors

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