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EHU049751

Sigma-Aldrich

MISSION® esiRNA

targeting human FEM1B

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

AGCTGATAAAATGGCGTGCTGCTATAGTAGTGAATGGCCATGGGATGACGCCATTGAAAGTAGCTGCCGAAAGCTGTAAAGCTGATGTCGTAGAACTGTTACTCTCTCATGCTGATTGCGACCGAAGAAGTCGGATTGAAGCTTTGGAACTCTTGGGTGCCTCCTTTGCAAATGACCGTGAGAACTATGACATCATAAAGACATACCACTATCTATATTTAGCCATGTTAGAGAGGTTCCAAGATGGTGATAACATTCTCGAAAAAGAGGTTCTTCCACCAATCCATGCTTATGGGAATAGAACTGAATGTAGAAATCCTCAGGAACTGGAGTCCATTCGGCAAGACAGAGATGCTCTTCATATGGAAGGCCTTATAGTTCGGGAACGGATTTTAGGTGCTGACAATATTGATGTTTCTCATCCCATCATTTACAGAGGAGCTGTTTATGCGGA

Ensembl | human accession no.

ENSG00000169018

NCBI accession no.

NM_015322

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... FEM1B(10116) , FEM1B(10116)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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John F Dankert et al.
Cell cycle (Georgetown, Tex.), 16(6), 556-564 (2017-01-25)
FEM1A, FEM1B, and FEM1C are evolutionarily-conserved VHL-box proteins, the substrate recognition subunits of CUL2-RING E3 ubiquitin ligase complexes. Here, we report that FEM1 proteins are ancient regulators of Stem-Loop Binding Protein (SLBP), a conserved protein that interacts with the stem
Keiichi Tamai et al.
Scientific reports, 10(1), 21592-21592 (2020-12-11)
Cancer stem cells (CSCs) define a subpopulation of cancer cells that are resistant to therapy. However, little is known of how CSC characteristics are regulated. We previously showed that dormant cancer stem cells are enriched with a CD274low fraction of

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