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Key Documents

D9408

Sigma-Aldrich

L-5,5-Dimethylthiazolidine-4-carboxylic acid

Synonym(s):

DTC

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About This Item

Empirical Formula (Hill Notation):
C6H11NO2S
CAS Number:
Molecular Weight:
161.22
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

assay

≥98% (TLC)

form

powder

color

white

storage temp.

2-8°C

SMILES string

CC1(C)SCN[C@@H]1C(O)=O

InChI

1S/C6H11NO2S/c1-6(2)4(5(8)9)7-3-10-6/h4,7H,3H2,1-2H3,(H,8,9)/t4-/m1/s1

InChI key

PMQQFSDIECYOQV-SCSAIBSYSA-N

Biochem/physiol Actions

L-5,5-Dimethylthiazolidine-4-carboxylic acid (DTC) is used as a proline analog with restricted conformation in studies on receptor bound conformational requirements for agonists and antagonists of angiotensin II (ANG II).

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Marloes Nies et al.
Thyroid : official journal of the American Thyroid Association, 30(8), 1169-1176 (2020-02-23)
Background: Differentiated thyroid carcinoma (DTC) during childhood is a rare disease. Its excellent survival rate requires a focus on
Anthony W DeMartino et al.
Chemical science, 8(10), 7186-7196 (2017-10-31)
We describe the kinetics of the formation and decay of a series of dithiocarbamates under physiological conditions. The goal is to provide a toolbox of compounds that release CS
Barbara Maria Szczerba et al.
Nature, 566(7745), 553-557 (2019-02-08)
A better understanding of the features that define the interaction between cancer cells and immune cells is important for the development of new cancer therapies1. However, focus is often given to interactions that occur within the primary tumour and its
Brigitte Decallonne et al.
European thyroid journal, 9(1), 32-39 (2020-02-20)
Regional variation in thyroid cancer incidence in Belgium, most pronounced for low risk cancer, was previously shown to be related to variation in clinical practice, with higher thyroid surgery rates and lower proportions of preoperative fine-needle aspiration (FNA) in regions
Wenjin Wang et al.
Biomedical optics express, 9(8), 3898-3914 (2018-10-20)
This paper introduces a new method to automate heart-rate detection using remote photoplethysmography (rPPG). The method replaces the commonly used region of interest (RoI) detection and tracking, and does not require initialization. Instead, it combines a number of candidate pulse-signals

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