D8886
Anti-Dehydroepiandrosterone (DHEA) antibody produced in rabbit
whole antiserum, lyophilized powder
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About This Item
biological source
rabbit
conjugate
unconjugated
antibody form
whole antiserum
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
technique(s)
radioimmunoassay: suitable
storage temp.
2-8°C
Immunogen
DHEA-15α-CH2-CO-BSA.
Biochem/physiol Actions
Dehydroepiandrosterone is a sulfated neurosteroid, abundantly present in the brain. It is a strong allosteric modulator of GABAA receptors and has antiseizure and anesthetic properties.
Reconstitution
Reconstitute with 11 ml 0.1 M phosphate buffered saline, pH 7.4, containing 0.1 M gelatin and 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Certificates of Analysis (COA)
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Journal of analytical toxicology, 35(9), 638-655 (2011-11-15)
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Behavioral and brain functions : BBF, 8, 61-61 (2012-12-21)
Neurosteroids are synthesized in the brain and modulate brain excitability. There is increasing evidence of their sedative, anesthetic and antiseizure properties, as well as their influence on mood. Currently neurosteroids are classified as pregnane neurosteroids (allopregnanolone and allotetrahydrodeoxycorticosterone), androstane neurosteroids
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