D2441

DcR3/Fc Chimera human

>90% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder

• Synonym(s): Decoy Receptor 3, M68, TR6
• MDL number: MFCD03702825
• UNSPSC Code: 12352200

Properties

• recombinant: expressed in baculovirus infected Sf21 cells
• assay: >90% (SDS-PAGE)
• form: lyophilized powder
• mol wt: glycosylated form 60-65 kDa by SDS-PAGE (reducing); calculated mol wt 57 kDa
• impurities: endotoxin, tested
• UniProt accession no.: O95407
• storage temp.: −20°C
• Gene Information: human ... TNFRSF6B(8771)

Description

Biochem/physiol Actions

DcR3 is a disulfide-linked homodimeric protein that is a member of the TNF receptor family. DcR3 modulates ligands that induce apoptosis.

Disulfide-linked homodimeric protein that is a member of the TNF receptor family; modulates ligands that induce apoptosis.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Analysis Note

Biological activity is measured by its ability to inhibit FAS-ligand induced apoptosis of Jurkat cells.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)