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D0286

Sigma-Aldrich

13,14-Dihydro-15-ketoprostaglandin E2 solution

~90%

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About This Item

Empirical Formula (Hill Notation):
C20H32O5
CAS Number:
363-23-5
Molecular Weight:
352.47
MDL number:
MFCD00135217
UNSPSC Code:
12352115
PubChem Substance ID:
329798596

assay

~90%

form

solution

shipped in

dry ice

storage temp.

−20°C

SMILES string

CCCCCC(=O)CC[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O

InChI

1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,16-17,19,23H,2-3,5-6,8-14H2,1H3,(H,24,25)/b7-4-/t16-,17-,19-/m1/s1

InChI key

CUJMXIQZWPZMNQ-XYYGWQPLSA-N

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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J E Brennand et al.
Prostaglandins, leukotrienes, and essential fatty acids, 58(5), 369-375 (1998-08-05)
This study aims to investigate potential mechanisms involved in the stimulatory effect of amniotic fluid on prostaglandin production by fetal membranes. A cell culture study of amnion and chorion was obtained following elective caesarean section, incubated with amniotic fluid collected
N Nishigaki et al.
Molecular pharmacology, 50(4), 1031-1037 (1996-10-01)
There are at least four subtypes of prostaglandin E (PGE) receptors. The EP1 and EP3 receptors are coupled to Ca2+ mobilization and the inhibition of adenylate cyclase, respectively, and the EP2 and EP4 receptors are coupled to the same signal
S Sakuma et al.
Prostaglandins, leukotrienes, and essential fatty acids, 51(6), 425-430 (1994-12-01)
The effect of 13-hydroperoxyoctadecadienoic acid (13-HPODE), a hydroperoxy adduct of linoleic acid (LA), on the activities of prostaglandin (PG) synthesizing and catabolizing enzymes in rabbit gastric antral mucosa was examined. 13-HPODE had no effect on the synthesis of PGE2, PGF2
Patricia A Thompson et al.
Cancer prevention research (Philadelphia, Pa.), 3(1), 101-107 (2010-01-07)
Regular use of nonsteroidal anti-inflammatory drugs (NSAID) has been associated with reduced risk of breast cancer. Sulindac, a nonselective NSAID with both cyclooxygenase-2-dependent and -independent activities, is a candidate for breast chemoprevention. We conducted a phase Ib trial in 30
B A Peskar et al.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 42(3), 327-331 (1991-09-01)
We have demonstrated recently the formation of a biologically active metabolite of prostaglandin (PG) E1, 13,14-dihydro-PGE1, during intravenous infusions of PGE1 in patients with peripheral arterial occlusive disease. We have now investigated the levels of the immediate precursor of 13,14-dihydro-PGE1
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