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CL6B200

Sigma-Aldrich

Sepharose™ CL-6B Size Exclusion Resin

Cross-linked, 90-350 mesh

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100 ML
$329.00
500 ML
$1,482.00

$329.00

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100 ML
$329.00
500 ML
$1,482.00

About This Item

CAS Number:
62610-50-8
MDL number:
MFCD00148280
UNSPSC Code:
23151817
NACRES:
NA.84

$329.00

Available to ship onMay 05, 2025Details

Request a Bulk Order
Notify Me

Get notified when this item is ready to ship via email.

Product Name

Sepharose™ CL-6B, Cross-linked

form

suspension

bead diameter

40-165 μm

pore size

10,000-1,000,000 fractionation range (Dextrans)
10,000-4,000,000 fractionation range (Globular proteins)

storage temp.

2-8°C

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General description

Sepharose CL is a cross-linked derivative of sepharose, prepared by reacting sepharose with 2,3-dibromopropanol under strongly alkaline conditions.[1]

Application

Sepharose CL-6B is used in affinity chromatography, protein chromatography, gel filtration chromatography, separation media and resins. Sepharose™ CL-6B has been used to study in vitro inhibition of human melanoma cells and to gather data in other valuable anticancer studies.
Sepharose™CL-6B has been used for the purification of glucoamylase enzyme[2] and targeted ribonucleoprotein (RNP)[3].

Legal Information

Sepharose is a trademark of Cytiva

replaced by

Product No.
Description
Pricing

pictograms

Flame
GHS02

signalword

Danger

hcodes

H225

Hazard Classifications

Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX7269
MKCX5420
MKCW0713
MKCW1843
MKCT8362

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W Chen et al.
Journal of bacteriology, 175(17), 5677-5682 (1993-09-01)
A membrane-associated ATPase with an M(r) of approximately 510,000 and containing subunits with M(r)s of 80,000 (alpha), 55,000 (beta), and 25,000 (gamma) was isolated from the methanogen Methanococcus voltae. Enzymatic activity was not affected by vanadate or azide, inhibitors of
Targeted Purification of RNA-Specific RNPs from Cell Lysates Through Immunoaffinity Precipitation to Identify Regulatory Proteins and RNAs
Beach DL and Keene JD
Methods in Molecular Biology, 69-69 (2008)
Eric Bertoft et al.
International journal of biological macromolecules, 49(4), 441-453 (2011-06-28)
The unit chains of amylopectin are organized into clusters. In this study, the cluster structure was analysed in detail in four different genotypes of barley, of which two possessed the amo1 genetic background. Amylose content of the barley starches differed
Rajendra K Sharma
Methods in molecular biology (Clifton, N.J.), 312, 325-342 (2005-01-01)
In general, the action of intracellular second messengers, 3':5'-cyclic adenosine monophosphate (cAMP) and 3':5'-cyclic guanosine monophosphate (cGMP), are terminated by cyclic nucleotide phosphodiesterase (PDE). In most mammalian tissues, PDE exists in multiple forms that differ in subcellular localization, catalytic, regulatory
Yihong Chen et al.
Se pu = Chinese journal of chromatography, 25(3), 332-336 (2007-08-08)
The S-type lectins in annelida are different in molecular structure and biochemical properties from that of common galectin and are valuable in anticancer study. Based on their specificity, Sepharose CL-6B affinity chromatography was adopted in this study to separate the
View All Related Papers

Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. セファロース™CL-6B(CAS 62610-50-8)はビーズには何も担持されていない無担持のものでしょうか？

    1 answer

    1. This is a product of Cytiva. The manufacturer notes that this matrix is a well-proven cross-linked agarose size exclusion chromatography base matrix and is frequently used for coupling affinity ligands to the matrix. The matrix is not pre-activated and the user performs all steps in coupling. The matrix contains 6% cross-linked agarose size exclusion chromatography resins. but there is no added functionality or support.

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