Human lymphoblastoid, Xeroderma pigmentosum complementation, EBV-transformed
Cell Line Description
Established by EBV transformation of mononuclear cells from a peripheral blood sample from a 30 year old male patient. The patient was diagnosed with Xeroderma pigmentosum complementation group A, a rare, autosomal recessive disorder with DNA-repair deficiency.
Application
Toxicity studies, hprt mutation analysis, study of DNA repair deficiencies
Maintain cultures between 3-9 x 100,000 cells/ml, dilute every 1-2 days to 3 x 100,000 cells/mls; 5% CO2; 37°C. Cells form floating aggregates.
Other Notes
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