JIM3 is a myeloma tumour line demonstrating typical plasma cell phenotype (CD38, PCA-1 8A and CD24 positive), deficient in DNA repair. JIM3 was derived from plasma myeloma cells derived from pleural fluid of advanced multiple myeloma patient, homoplastic with JIM1. Used for in vitro study and comparison of genetic instability in myeloma tumour lines (homoplastic with JIM1) and the in vitro study of effects of DNA repair deficiency in myeloma tumour lines
DNA Profile
Not specified
Culture Medium
Dexter culture medium, consisting of Fischer′s medium + 20% FCS +10-7 M hydrocortisone sodium succinate
Subculture Routine
Seed at 2-9 x 105 cells/cm3 5% CO2; 37 °C.
Other Notes
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Disclaimer
This cell line has special release conditions: Commercial organisations are required to complete the ′Cell Line Release Authorisation for Research Use in Commercial Organisations′ release conditions form.
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