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COV434

NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA.

Synonym(s):

COV-434 Cells

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About This Item

UNSPSC Code:
41106514
Pricing and availability is not currently available.

biological source

human ovary

packaging

tube of 5 μg 07071909-DNA-5UG
pkg of vial of cells 07071909-1VL

growth mode

Adherent

karyotype

Modal chromosome no. 47 (46 - 47)

morphology

Polygonal & fusiform

products

Not specified

receptors

Not specified

technique(s)

cell culture | mammalian: suitable

relevant disease(s)

cancer

shipped in

dry ice

storage temp.

−196°C

Cell Line Origin

Human ovarian granulosa tumour

Cell Line Description

Human ovarian granulosa tumour cell line established from a solid primary tumour.

Application

COV434 has been used to study:
  • the effect of 17β-estradiol on granulosa cell tumor growth, migration and invasion[1]
  • if mutant p53 (inactivatible R248Q hotspot mutation) works as a cancer-specific drug target[2]
  • the expression of TLR (toll-like receptor) and its function in the cell line[3]

Culture Medium

DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS)

Subculture Routine

Split confluent cultures 1:2 to 1:5 i.e. seeding at 2-4x10,000 cells/cm2 using trypsin/EDTA; 5% CO2; 37°C.

Other Notes

Additional freight & handling charges may be applicable for Asia-Pacific shipments. Please check with your local Customer Service representative for more information.

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Questions

  1. Is the COV434 granulosa cell line immortalized or not?

    1 answer

    1. Yes, this cell line is isolated from ovarian tumor; therefore it is an immortalized cell line.

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