C8464

Monoclonal Anti-CD22 antibody produced in mouse

clone HIB22, purified immunoglobulin, buffered aqueous solution

• Synonym(s): Monoclonal Anti-CD22
• UNSPSC Code: 12352203

Properties

• biological source: mouse
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: HIB22, monoclonal
• form: buffered aqueous solution
• mol wt: antigen 135 kDa
• species reactivity: human
• technique(s): flow cytometry: 5 μL using 1 × 10⁶ cells; immunohistochemistry (frozen sections): suitable
• isotype: IgG1
• UniProt accession no.: P20273
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: human ... CD22(933)

Description

Specificity

Recognizes the CD22, 135 kDa transmembrane phosphoglycoprotein. The antibody may be used for detection of both membrane and cytoplasmic CD22 and is suitable for flow cytometry and for staining of acetone-fixed, frozen tissue sections. It binds to an epitope dependent on the presence of both the first and the second Ig-like domains of the CD22 molecule. It does not inhibit CD22 mediated adhesion of various cells to CD22 transfected lines.
5th Workshop: Code No. CD22.14.

Immunogen

hairy cell leukemia cells.

Target description

CD22 belongs to the immunoglobulin superfamily. It is expressed on the surface of mature B cells and in the cytoplasm of virtually all B cells but not plasma cells. CD22 is strongly expressed in hairy cell leukemia cells.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.