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C8105

Sigma-Aldrich

Phytoceramide C2

98% (TLC)

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About This Item

Empirical Formula (Hill Notation):
C20H41NO4
Molecular Weight:
359.54
MDL number:
MFCD02686954
UNSPSC Code:
12352211
PubChem Substance ID:
24893024

assay

98% (TLC)

form

solid

solubility

DMSO: >25 mg/mL (with warming)
ethanol: >25 mg/mL

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@H](CO)NC(C)=O

InChI

1S/C20H41NO4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19(24)20(25)18(16-22)21-17(2)23/h18-20,22,24-25H,3-16H2,1-2H3,(H,21,23)/t18-,19+,20-/m0/s1

InChI key

SZUJJDLBXJCDNT-ZCNNSNEGSA-N

Biochem/physiol Actions

Yeast growth inhibitor and ceramide-activated protein phosphatase (CAPP) activator.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
021K1298
021K1297

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J D Fishbein et al.
The Journal of biological chemistry, 268(13), 9255-9261 (1993-05-05)
Ceramide is emerging as a potential physiologic regulator of growth and differentiation in mammalian cells. This regulation may be mediated through the action of a serine/threonine ceramide-activated protein phosphatase (CAPP). In this study, the existence of a ceramide-mediated pathway of
J S Lee et al.
FEBS letters, 499(1-2), 82-86 (2001-06-22)
Sphingolipid metabolites, such as sphingosine and ceramide, are known to play important roles in cell proliferation, differentiation and apoptosis, but the physiological roles of phytosphingosine (PHS) and phytoceramide (PHC) are poorly understood. In this study we investigated the effects of

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