C7742

Monoclonal Anti-CMKLR1 antibody produced in rat

~1.5 mg/mL, clone BZ332, purified immunoglobulin, buffered aqueous solution

• Synonym(s): Anti-BLTR, Anti-ChemR23, Anti-Chemerin Receptor, Anti-ChemerinR, Anti-Chemokine-like Receptor 1, Anti-G Protein-coupled Receptor 16, Anti-GPR16, Anti-LTB4R, Anti-Leukotriene B4 G Protein-coupled Receptor, Anti-Leukotriene B4 Receptor, Anti-P2RY7, Anti-Purinergic Receptor P2Y, G protein-coupled, 7, Anti-Purinoceptor P2Y7
• MDL number: MFCD08705578
• UNSPSC Code: 12352203

Properties

• biological source: rat
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: BZ332, monoclonal
• form: buffered aqueous solution
• species reactivity: mouse, human
• concentration: ~1.5 mg/mL
• technique(s): flow cytometry: 10-20 μg/mL using EL4 mouse lymphoma cells
• isotype: IgG2aκ
• UniProt accession no.: Q99788
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: human ... CMKLR1(1240) ; mouse ... Cmklr1(14747)

Description

Immunogen

peptide corresponding to amino acids 8-32 at the N-terminal region of human CMKLR1, conjugated to KLH.

Application

Monoclonal Anti-CMKLR1 antibody produced in rat is suitable for flow cytometry at a concentration of 10-20μg/mL using EL4 mouse lymphoma cells.

Biochem/physiol Actions

Chemokine receptor-like 1 (CMLKR1), also known as ChemR23 (Chemerin Receptor 23), is a protein encoded by the CMKLR1 gene in humans. It encodes a protein that is structurally homologous to the seven transmembrane G-protein linked chemokine receptors. CMLKR1 is localized to human chromosome 12q24.1.[1] Chemerin acting through its distinct G protein-coupled receptor CMKLR1 is a novel adipokine. Its circulating levels are increased in inflammatory states.[2]

Physical form

Soluton in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)