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C7366

Sigma-Aldrich

Anti-Cholesteryl Ester Transfer Protein (CETP) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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About This Item

MDL number:
UNSPSC Code:
12352203

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

western blot: 2 μg/mL using human liver extracts

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CETP(1071)

Immunogen

synthetic peptide corresponding to amino acid residues 140-151 of the human CETP protein.

Application

Anti-Cholesteryl Ester Transfer Protein (CETP) antibody produced in rabbit is suitable for western blotting at a concentration of 2μg/mL using human liver extracts.

Biochem/physiol Actions

Cholesteryl ester transfer protein (CETP) is also called plasma lipid transfer protein. It is encoded by CETP gene. It is a plasma protein that helps in the transport of cholesteryl esters and triglycerides between the lipoproteins. CETP is an important regulator of plasma high-density lipoprotein cholesterol (HDL-C). It plays an important role in reverse cholesterol and is involved in metabolism of high-density lipoprotein cholesterol. Its deficiency is a unique plasma lipoprotein profile without any symptoms and is common in East Asia. It may act as a candidate gene for human longevity.

Physical form

Solution in phosphate buffered saline containing 1.0 mg/mL BSA and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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Shinji Yokoyama
Biochimica et biophysica acta, 1841(4), 495-504 (2014-01-07)
Cholesteryl ester transfer protein (CETP)-deficiency manifests a unique plasma lipoprotein profile without other apparent symptoms. It is highly common in East Asia while rather rare anywhere else. A potential environmental screening factor(s) may therefore contribute to this eccentric distribution, such
Adam Suhy et al.
Biochemical and biophysical research communications, 443(4), 1270-1274 (2014-01-08)
Cholesteryl ester transfer protein (CETP) plays an important role in reverse cholesterol transport, with decreased CETP activity increasing HDL levels. Formation of an alternative splice form lacking exon 9 (Δ9-CETP) has been associated with two single nucleotide polymorphisms (SNPs) in
Jun Wang et al.
Lipids in health and disease, 12, 176-176 (2013-11-29)
Coronary atherosclerosis, the most common form of coronary artery disease (CAD), is characterized by accumulation of lipid in the walls of coronary arteries. Recent data from clinical trials have showed that high-density lipoprotein cholesterol (HDL-C) has causal role in the
Jian-Kang Yang et al.
Molecular biology reports, 41(1), 325-329 (2013-11-19)
The cholesteryl ester transfer protein (CETP), which is involved in the regulation of reverse cholesterol transport and metabolism of high-density lipoprotein cholesterol, has been proposed as a candidate gene for human longevity. SNPs in the promoter region of the CETP

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