C6990
Anti-phospho-c-Met (pTyr1349) antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
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About This Item
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
western blot: 1:1000
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... MET(4233)
General description
c-Met is a protein that belongs to Tyr protein kinase family. It has a pivotal role in various physiological processes like scattering, morphogenesis and proliferation. C-Met (Tyr1349) is the principal docking site for PI 3-kinase and GAB1. Phosphorylation of (Tyr1349) and (Tyr1356) is crucial for protein binding. Rabbit anti-phospho-c-Met (pTyr1349) antibody reacts specifically with c-Met (pTyr1349) from human.
Immunogen
synthetic phosphopeptide derived from the region of c-Met that contains tyrosine 1349.
Application
Anti-phospho-c-Met (pTyr1349) antibody can be used in western blotting (diluted 1:1000).
Physical form
Solution in Dulbecco′s phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, with 1.0 mg/mL BSA (IgG and protease free), 50% glycerol and 0.05% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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A Nusrat et al.
The Journal of clinical investigation, 93(5), 2056-2065 (1994-05-01)
Intestinal epithelial cells rest on a fibroblast sheath. Thus, factors produced by these fibroblasts may influence epithelial function in a paracrine fashion. We examined modulation of intestinal epithelial function by one such fibroblast product, scatter factor/hepatocyte growth factor (HGF/SF). This
D P Bottaro et al.
Science (New York, N.Y.), 251(4995), 802-804 (1991-02-15)
Hepatocyte growth factor (HGF) is a plasminogen-like protein thought to be a humoral mediator of liver regeneration. A 145-kilodalton tyrosyl phosphoprotein observed in rapid response to HGF treatment of intact target cells was identified by immunoblot analysis as the beta
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