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C6488

Sigma-Aldrich

Anti-Calcium Channel (γ5 subunit) antibody produced in rabbit

~1 mg/mL, fractionated antiserum, buffered aqueous solution

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About This Item

MDL number:
MFCD05865338
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

fractionated antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, rat, mouse

concentration

~1 mg/mL

technique(s)

western blot: 5-10 μg/mL using rat brain lysate

UniProt accession no.

Q9UF02

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... CACNG5(27091)
mouse ... Cacng5(140723)
rat ... Cacng5(140726)

Immunogen

synthetic peptide derived from the rat calcium channel γ5 subunit conjugated to KLH.

Application

Anti-Calcium Channel (γ5 subunit) antibody produced in rabbit is suitable for western blotting at a concentration of 5-10μg/mL using rat brain lysate.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)

Biochem/physiol Actions

CACNG5 gene encodes a type II transmembrane AMPA receptor regulatory protein (TARP). The calcium channel γ subunits consist of eight-member protein family that shares a common topology consisting of four transmembrane domains and intracellular N- and C-termini. CACNG5 plays a key role for voltage-dependent calcium channel in the susceptibility to bipolar disorder and/or schizophrenia.

Physical form

Solution in phosphate buffered saline containing 0.08% sodium azide.

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Storage Class

10 - Combustible liquids

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Certificates of Analysis (COA)

Lot/Batch Number
128K1472
114K1291
083K0726

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David Curtis et al.
Psychiatric genetics, 21(1), 1-4 (2010-11-09)
There are theoretical reasons why comparing marker allele frequencies between cases of different diseases, rather than with controls, may offer benefits. The samples may be better matched, especially for background risk factors common to both diseases. Genetic loci may also
Ren-Shiang Chen et al.
Cell biochemistry and biophysics, 47(2), 178-186 (2007-07-27)
The calcium channel gamma subunits comprise an eight-member protein family that share a common topology consisting of four transmembrane domains and intracellular N- and C-termini. Although the first gamma subunit was identified as an auxiliary subunit of a voltage-dependent calcium
Marzieh Zonouzi et al.
Nature neuroscience, 14(11), 1430-1438 (2011-10-11)
Oligodendrocyte precursor cells (OPCs), a major glial cell type that gives rise to myelinating oligodendrocytes in the CNS, express calcium-permeable AMPA receptors (CP-AMPARs). Although CP-AMPARs are important for OPC proliferation and neuron-glia signaling, they render OPCs susceptible to ischemic damage

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