C6322
Chorionic gonadotropin human
recombinant, expressed in mouse cell line, lyophilized powder
Synonym(s):
Choriogonin, HCG
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About This Item
form:
lyophilized powder
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recombinant
expressed in mouse cell line
form
lyophilized powder
potency
≥10,000 I.U. per mg
mol wt
37.9 kDa
apparent mol wt 56.8 kDa by SDS-PAGE
drug control
Home Office Schedule 4.2
solubility
water: 1 mg/mL, clear, colorless
UniProt accession no.
shipped in
ambient
storage temp.
−20°C
Gene Information
human ... CGA(1081)
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General description
Glycoprotein hormone consisting of a 92-amino acid α-chain which is identical to that of LH, FSH, and TSH; and a distinct 149-amino acid β-chain. Produced by chorionic tissue and responsible for maintaining the corpus luteum during early pregnancy. Also produced by trophoblast cell neoplasms, which are marked by elevated free hCG β-chains and hyperglycosylated hCG.
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Thi-Mong Diep Nguyen et al.
General and comparative endocrinology, 261, 23-30 (2018-01-23)
We have compared various Luteinizing Hormone (LH) and Chorionic Gonadotropin (CG) preparations from non-human and human species in their ability to synergize with 10 µM forskolin (FSK) for cyclic AMP intracellular accumulation, in MLTC cells. LH from rat pituitary as well
Bridget A Quinn et al.
PloS one, 4(12), e8404-e8404 (2010-01-05)
Approximately one out of every ten cases of epithelial ovarian cancer (EOC) is inherited. The majority of inherited cases of EOC result from mutations in the breast cancer associated gene 1 (BRCA1). In addition to mutation of BRCA1, mutation of
Damian B Yap et al.
PloS one, 6(11), e27127-e27127 (2011-11-10)
Mll5 is currently a member of the Mll family of SET domain histone methyltransferase proteins but studies have also showed that it could be part of the SET3 branch of proteins. Recently, constitutive knock out animal studies have shown that
Corine K Lau et al.
Molecular biology of the cell, 20(18), 4043-4058 (2009-07-31)
Mitosis in higher eukaryotes is marked by the sequential assembly of two massive structures: the mitotic spindle and the nucleus. Nuclear assembly itself requires the precise formation of both nuclear membranes and nuclear pore complexes. Previously, importin alpha/beta and RanGTP
Mary E Sabatini et al.
Journal of ovarian research, 4(1), 8-8 (2011-05-25)
Metformin, an oral biguanide traditionally used for the treatment of type 2 diabetes, is widely used for the management of polycystic ovary syndrome (PCOS)-related anovulation. Because of the significant prevalence of insulin resistance and glucose intolerance in PCOS patients, and
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