C5367

Monoclonal Anti-Casein Kinase 2α antibody produced in mouse

~2 mg/mL, clone 1AD9, purified immunoglobulin, buffered aqueous solution

• Synonym(s): Anti-CK2α
• MDL number: MFCD00675214
• UNSPSC Code: 12352203

Properties

• biological source: mouse
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 1AD9, monoclonal
• form: buffered aqueous solution
• mol wt: antigen ~35 kDa
• species reactivity: rat, mouse, human
• concentration: ~2 mg/mL
• technique(s): immunoprecipitation (IP): suitable; indirect ELISA: suitable; microarray: suitable; western blot: 2-4 μg/mL using total cell extract of MCF7 cells.
• isotype: IgG1
• UniProt accession no.: P68400
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... CSNK2A1(1457) ; mouse ... Csnk2a1(12995) ; rat ... Csnk2a1(116549)

Description

General description

CK2 is a ubiquitously expressed serine/threonine kinase that has been implicated in various cellular functions such as cell death, cell cycle regulation, and mRNA synthesis. This protein kinase comprises of two catalytic α subunits and two dimeric β subunits that associate to form a heterotetrameric enzyme complex.CK2 is also involved in regulating viral infections . Monoclonal Anti-Casein Kinase 2α antibody is specific for casein kinase 2 α in humans, rats and mice (approx. 35 kDa). The antibody-binding epitope resides within amino acids 319-324 of human CK2α. This epitope is conserved across several species.

Immunogen

human denatured recombinant casein kinase 2α.

Application

Monoclonal Anti-Casein Kinase 2α antibody is suitable for use in immunoprecipitation and western blot assays using human fibroblasts . The product can also be used for indirect ELISA and microarray applications.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.