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C3196

S(−)-Cathinone hydrochloride

Synonym(s):

α-Aminopropiophenone hydrochloride, S(−)-2-Amino-1-phenyl-1-propanone hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C9H11NO · HCl
CAS Number:
Molecular Weight:
185.65
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Form:
powder
Quality level:

form

powder

Quality Level

drug control

USDEA Schedule I; Home Office Schedule 1; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal), kontrollierte Droge in Deutschland

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

solubility

H2O: soluble, ethanol: soluble

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

storage temp.

2-8°C

SMILES string

Cl.C[C@H](N)C(=O)c1ccccc1

InChI

1S/C9H11NO.ClH/c1-7(10)9(11)8-5-3-2-4-6-8;/h2-7H,10H2,1H3;1H/t7-;/m0./s1

InChI key

HPZCAKYHISJOIK-FJXQXJEOSA-N

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1 of 1

This Item
C222M8750M6267
form

powder

form

powder

form

-

form

-

drug control

USDEA Schedule I; Home Office Schedule 1; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

drug control

USDEA Schedule IV; Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

drug control

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

drug control

USDEA Schedule I; Home Office Schedule 1; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

-

solubility

H2O: soluble, ethanol: soluble

solubility

H2O: 15 mg/mL, clear, 0.1 M HCl: soluble, ethanol: soluble

solubility

H2O: soluble, ethanol: soluble

solubility

H2O: soluble

General description

Cathinone is a monoamine alkaloid of Khat shrub. It is a β-keto derivative of amphetamine. Cathinone is structurally similar to dopamine and amphetamine. A synthetic cathinone is categorized as a new psychoactive substance.[1]

Biochem/physiol Actions

Cathinone is the major central nervous system stimulant. Like amphetamine, it is a potent releaser of norepinephrine and dopamine from their intracellular stores. Cathinone derivates are known to have prolonged effects on nervous and blood vascular systems. The mode of action of its derivative is by inhibiting the reuptake of neurotransmitters and stimulating cathinone-sensitive receptors.[1]

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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A E Fleckenstein et al.
European journal of pharmacology, 382(1), 45-49 (1999-11-11)
High-dose administrations of amphetamine, methamphetamine, cathinone, methcathinone or methylenedioxymethamphetamine rapidly decrease dopamine and serotonin transporter function in vivo, as assessed in striatal synaptosomes obtained from drug-treated rats. In contrast, high-dose injections of fenfluramine, cocaine or methylphenidate had little or no
D J Calcagnetti et al.
Progress in neuro-psychopharmacology & biological psychiatry, 17(4), 637-649 (1993-07-01)
1. The objective of Exp. 1 was to determine whether intracerebroventricular (ICV) injection of cathinone CATH (8.0-32 micrograms) would produce a dose-dependent conditioned place preference (CPP) and/or activation in rats. Results indicate that rats conditioned with 16 or 32 micrograms
Issues of false negative results in toxicology: difficult in detecting certain drugs and issues with detection of synthetic cathinone (bath salts), synthetic cannabinoids (spice), and other new psychoactive substances
Accurate Results in the Clinical Laboratory: A Guide to Error Detection and Correction, 257-270 (2019)
E A Pehek et al.
Neuropharmacology, 29(12), 1171-1176 (1990-12-01)
The effects of (-)cathinone, the primary psychoactive alkaloid of the Khat plant, were compared to those of (+)amphetamine in the anterior caudate-putamen and the nucleus accumbens. In vivo microdialysis was used to measure extracellular levels of dopamine and metabolites in
P Kalix et al.
Biochemical pharmacology, 35(18), 3015-3019 (1986-09-15)
The alkaloid (-)cathinone is a potent stimulant with pharmacological properties closely resembling those of (+)amphetamine. Since (-)cathinone is capable of inducing release at physiological catecholamine storage sites, it has been suggested that (-)cathinone and (+)amphetamine have the same mechanism of

Global Trade Item Number

SKUGTIN
C3196-50MG04061832556208
C3196-10MG04061832556192

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