C212100

DMT-2′O-Methyl-rC(tac) Phosphoramidite

• Synonym(s): DMT-2′-O-Me-rC(tac) amidite, N-[[4-(1,1-dimethylethyl)phenoxy]acetyl]-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-cytidine, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
• Empirical Formula (Hill Notation): C₅₂H₆₄N₅O₁₀P
• CAS Number: 179486-26-1
• Molecular Weight: 950.07
• MDL number: MFCD09842120
• UNSPSC Code: 41116105
• PubChem Substance ID: 329774939

Properties

• product line: Proligo Reagents
• assay: ≥98.0% (reversed phase HPLC); ≥99% (³¹P-NMR)
• form: solid
• technique(s): oligo synthesis: suitable
• λ: conforms (UV/VIS Identity)
• nucleoside profile: base: cytidine; base protecting group: TAC; 2' protecting group: methyl; 5' protecting group: DMT; deprotection: fast
• storage temp.: −20°C
• SMILES string: CO[C@@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(c2ccccc2)(c3ccc(OC)cc3)c4ccc(OC)cc4)O[C@H]1N5C=CC(NC(=O)COc6ccc(cc6)C(C)(C)C)=NC5=O
• InChI: 1S/C52H64N5O10P/c1-35(2)57(36(3)4)68(65-32-14-30-53)67-47-44(33-64-52(38-15-12-11-13-16-38,39-19-23-41(60-8)24-20-39)40-21-25-42(61-9)26-22-40)66-49(48(47)62-10)56-31-29-45(55-50(56)59)54-46(58)34-63-43-27-17-37(18-28-43)51(5,6)7/h11-13,15-29,31,35-36,44,47-49H,14,32-34H2,1-10H3,(H,54,55,58,59)/t44-,47-,48-,49-,68?/m1/s1
• InChI key: JRJMGDLRRSEUHM-MVHRPHEDSA-N

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable