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C2047

Sigma-Aldrich

Chorionic gonadotropin human

suitable for radioiodination, RIA, lyophilized powder

Synonym(s):

Choriogonin, HCG

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352200

sterility

sterile-filtered

form

lyophilized powder

potency

~13,000 I.U. per mg

mol wt

37.9 kDa

drug control

Home Office Schedule 4.2

impurities

HBV,HCV and HIV, tested negative

solubility

water: soluble

suitability

suitable for radioiodination, RIA

UniProt accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... CGA(1081)

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General description

Glycoprotein hormone consisting of a 92-amino acid α-chain which is identical to that of LH, FSH, and TSH; and a distinct 149-amino acid β-chain. Produced by chorionic tissue and responsible for maintaining the corpus luteum during early pregnancy. Also produced by trophoblast cell neoplasms, which are marked by elevated free hCG β-chains and hyperglycosylated hCG.

Physical form

Lyophilized from a solution containing 1 mg per mL in 0.1 M ammonium bicarbonate buffer, pH 7.0.

pictograms

Health hazard

signalword

Warning

hcodes

pcodes

Hazard Classifications

Repr. 2

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Yohei Shirai et al.
The Journal of reproduction and development, 55(3), 240-246 (2009-02-24)
To investigate molecular effects of anti-sperm autoantibodies on fertilization, we previously established anti-mouse sperm-head auto-monoclonal antibodies (mAbs). Among the mAbs established, one mAb (named Ts4) recognized the sugar moiety of TEX101, a germ cell-marker glycoprotein. In the present study, we
Damian B Yap et al.
PloS one, 6(11), e27127-e27127 (2011-11-10)
Mll5 is currently a member of the Mll family of SET domain histone methyltransferase proteins but studies have also showed that it could be part of the SET3 branch of proteins. Recently, constitutive knock out animal studies have shown that
Bridget A Quinn et al.
PloS one, 4(12), e8404-e8404 (2010-01-05)
Approximately one out of every ten cases of epithelial ovarian cancer (EOC) is inherited. The majority of inherited cases of EOC result from mutations in the breast cancer associated gene 1 (BRCA1). In addition to mutation of BRCA1, mutation of
Corine K Lau et al.
Molecular biology of the cell, 20(18), 4043-4058 (2009-07-31)
Mitosis in higher eukaryotes is marked by the sequential assembly of two massive structures: the mitotic spindle and the nucleus. Nuclear assembly itself requires the precise formation of both nuclear membranes and nuclear pore complexes. Previously, importin alpha/beta and RanGTP
Mary E Sabatini et al.
Journal of ovarian research, 4(1), 8-8 (2011-05-25)
Metformin, an oral biguanide traditionally used for the treatment of type 2 diabetes, is widely used for the management of polycystic ovary syndrome (PCOS)-related anovulation. Because of the significant prevalence of insulin resistance and glucose intolerance in PCOS patients, and

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