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C1853

Sigma-Aldrich

Anti-Calcium Channel (α1E Subunit) (R-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

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About This Item

MDL number:
UNSPSC Code:
12352203

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

rat

technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot (chemiluminescent): 1:200-1:400 using rat brain membranes

UniProt accession no.

storage temp.

−20°C

Gene Information

Immunogen

synthetic peptide corresponding to amino acids 892-907 of the α1E subunit of rat brain voltage-gated calcium channel (VGCC, CNE1) with additional N-terminal cysteine, conjugated to KLH.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunoprecipitation (1 paper)

Physical form

Lyophilized at ~0.3 mg/ml from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, 5% sucrose and 0.025% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Yuqi Ren et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 42(9), 1648-1665 (2022-01-13)
GABAB receptors in habenula cholinergic neurons mediate strong presynaptic excitation and control aversive memory expression. K+ channel tetramerization domain (KCTD) proteins are key interacting partners of GABAB receptors; it remains unclear whether and how KCTDs contribute to GABAB excitatory signaling.
Lucian Medrihan et al.
Nature communications, 4, 1512-1512 (2013-02-28)
In the central nervous system, most synapses show a fast mode of neurotransmitter release known as synchronous release followed by a phase of asynchronous release, which extends over tens of milliseconds to seconds. Synapsin II (SYN2) is a member of

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